Effectiveness and safety of bronchodilators and inhaled corticosteroids in the management of chronic obstructive pulmonary disease
نویسندگان
چکیده
Chronic obstructive pulmonary disease (COPD) is a lung condition marked by restricted airflow. It globally prevalent affecting almost 300 million individuals. COPD linked to significant burden of morbidity and mortality thus necessitating early diagnosis management. Rising treatment options complicate care necessitate review clinical data guide choices. Corticosteroids bronchodilators are the mainstay for due their safety efficacy. Compared inhaled corticosteroids or long-acting β-agonist therapy alone, plus lower risk exacerbations enhance function health status in patients with COPD. Patients who experience frequent despite taking those have evidence eosinophilic bronchial inflammation, as shown high blood eosinophil levels and/or history asthma asthma-COPD overlap, may both benefit greatly from therapy. Although not widespread, corticosteroid use an elevated pneumonia vary depending on particular utilized. Recent research combination has advantages supports its widespread however some studies trials also demonstrated quite conflicting outcomes this therefore need further exhibit conclusive results. The purpose available information about effectiveness management
منابع مشابه
CHRONIC OBSTRUCTIVE PULMONARY DISEASE Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease
D D Sin, L Wu, J A Anderson, N R Anthonisen, A S Buist, P S Burge, P M Calverley, J E Connett, B Lindmark, R A Pauwels , D S Postma, J B Soriano, W Szafranski, J Vestbo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کامل[Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease].
BACKGROUND Clinical studies suggest that inhaled corticosteroids reduce exacerbations and improve health status in chronic obstructive pulmonary disease (COPD). However, their effect on mortality is unknown. METHODS A pooled analysis, based on intention to treat, of individual patient data from seven randomised trials (involving 5085 patients) was performed in which the effects of inhaled cor...
متن کاملCardiovascular safety of inhaled long-acting bronchodilators in individuals with chronic obstructive pulmonary disease.
IMPORTANCE Chronic obstructive pulmonary disease (COPD) is a common and deadly disease. Long-acting inhaled β-agonists and anticholinergics, first-line medications for COPD, have been associated with increased risk of cardiovascular outcomes. When choosing between the medications, patients and physicians would benefit from knowing which has the least risk. OBJECTIVE To assess the association ...
متن کاملDetermination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease
Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.Materials & Methods: This cross-sectional study was conducted on adult patients with forced...
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ژورنال
عنوان ژورنال: International Journal of Community Medicine and Public Health
سال: 2023
ISSN: ['2394-6032', '2394-6040']
DOI: https://doi.org/10.18203/2394-6040.ijcmph20232392